Compile Data Set for Download or QSAR
Found 79 of Enz. Inhib. data with enzyme = 'Peptidyl-prolyl cis-trans isomerase FKBP1A' and Substrate = 'BDBM23318'
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23334(3-(pyridin-3-yl)propyl (2S)-1-(3,3-dimethyl-2-oxop...)copy SMILEScopy InChI
Affinity DataKi:  7.5nM ΔG°:  -10.1kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23319(3,3-dimethyl-1-[(2S)-2-(5-phenylpentanoyl)pyrrolid...)copy SMILEScopy InChI
Affinity DataKi:  30nM ΔG°:  -9.40kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9G7GPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23346(1-{4,6-dimethoxy-12-oxo-11,17-diazatetracyclo[11.3...)copy SMILEScopy InChI
Affinity DataKi:  34nM ΔG°:  -9.84kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23345(1-(3,4-dichlorophenyl)-2-{4,6-dimethoxy-12-oxo-11,...)copy SMILEScopy InChI
Affinity DataKi:  34nM ΔG°:  -9.84kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23347(1-(3-chlorophenyl)-2-{4,6-dimethoxy-12-oxo-11,17-d...)copy SMILEScopy InChI
Affinity DataKi:  46nM ΔG°:  -9.67kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23397(4-(3,5-dimethoxyphenyl)-13-[2-oxo-2-(3,4,5-trimeth...)copy SMILEScopy InChI
Affinity DataKi:  54nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23372(17-[(3-bromobenzene)sulfonyl]-4,6-dimethoxy-11,17-...)copy SMILEScopy InChI
Affinity DataKi:  54nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23348(1-{4,6-dimethoxy-12-oxo-11,17-diazatetracyclo[11.3...)copy SMILEScopy InChI
Affinity DataKi:  60nM ΔG°:  -9.52kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23335(1-{4,6-dimethoxy-12-oxo-11,17-diazatetracyclo[11.3...)copy SMILEScopy InChI
Affinity DataKi:  69nM ΔG°:  -9.44kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23349(1-(4-bromophenyl)-2-{4,6-dimethoxy-12-oxo-11,17-di...)copy SMILEScopy InChI
Affinity DataKi:  71nM ΔG°:  -9.42kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23350(1-(4-chlorophenyl)-2-{4,6-dimethoxy-12-oxo-11,17-d...)copy SMILEScopy InChI
Affinity DataKi:  72nM ΔG°:  -9.41kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23373(4-({4,6-dimethoxy-12-oxo-11,17-diazatetracyclo[11....)copy SMILEScopy InChI
Affinity DataKi:  82nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23374(4,6-dimethoxy-17-[(4-methylbenzene)sulfonyl]-11,17...)copy SMILEScopy InChI
Affinity DataKi:  84nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23336(1-{5-methyl-12-oxo-11,17-diazatetracyclo[11.3.1.0^...)copy SMILEScopy InChI
Affinity DataKi:  85nM ΔG°:  -9.32kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23375(4,6-dimethoxy-17-[(4-phenylbenzene)sulfonyl]-11,17...)copy SMILEScopy InChI
Affinity DataKi:  88nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23365(17-[2,2-difluoro-2-(3,4,5-trimethoxyphenyl)acetyl]...)copy SMILEScopy InChI
Affinity DataKi:  91nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23376(17-[(4-bromobenzene)sulfonyl]-4,6-dimethoxy-11,17-...)copy SMILEScopy InChI
Affinity DataKi:  92nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23351(1-{4,6-dimethoxy-12-oxo-11,17-diazatetracyclo[11.3...)copy SMILEScopy InChI
Affinity DataKi:  100nM ΔG°:  -9.22kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23377(4,6-dimethoxy-17-[(3-methylbenzene)sulfonyl]-11,17...)copy SMILEScopy InChI
Affinity DataKi:  104nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23337(1-{7-methoxy-12-oxo-11,17-diazatetracyclo[11.3.1.0...)copy SMILEScopy InChI
Affinity DataKi:  105nM ΔG°:  -9.19kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23367(1-{4,6-dimethoxy-12-oxo-11,17-diazatetracyclo[11.3...)copy SMILEScopy InChI
Affinity DataKi:  107nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23368(1-{4,6-dimethoxy-12-oxo-11,17-diazatetracyclo[11.3...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23352(1-{4,6-dimethoxy-12-oxo-11,17-diazatetracyclo[11.3...)copy SMILEScopy InChI
Affinity DataKi:  110nM ΔG°:  -9.17kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23369(1-{4,6-dimethoxy-12-oxo-11,17-diazatetracyclo[11.3...)copy SMILEScopy InChI
Affinity DataKi:  114nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23387(17-{[(2R,6S)-2,6-dimethylmorpholine-4-]sulfonyl}-6...)copy SMILEScopy InChI
Affinity DataKi:  123nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23353(1-{4,6-dimethoxy-12-oxo-11,17-diazatetracyclo[11.3...)copy SMILEScopy InChI
Affinity DataKi:  123nM ΔG°:  -9.10kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23338(1-{5-chloro-12-oxo-11,17-diazatetracyclo[11.3.1.0^...)copy SMILEScopy InChI
Affinity DataKi:  126nM ΔG°:  -9.09kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23322(3,3-dimethyl-1-[(2S)-2-{5-[2,3,5,6-tetrafluoro-4-(...)copy SMILEScopy InChI
Affinity DataKi:  130nM ΔG°:  -8.60kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9G7GPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23354(1-{4,6-dimethoxy-12-oxo-11,17-diazatetracyclo[11.3...)copy SMILEScopy InChI
Affinity DataKi:  131nM ΔG°:  -9.07kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23339(1-{6-methoxy-12-oxo-11,17-diazatetracyclo[11.3.1.0...)copy SMILEScopy InChI
Affinity DataKi:  143nM ΔG°:  -9.02kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23388(N-(3,4-difluorophenyl)-6-methoxy-12-oxo-11,17-diaz...)copy SMILEScopy InChI
Affinity DataKi:  150nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23340(1-{7-chloro-12-oxo-11,17-diazatetracyclo[11.3.1.0^...)copy SMILEScopy InChI
Affinity DataKi:  152nM ΔG°:  -8.98kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23378(17-{[4-(3,4-dichlorophenyl)benzene]sulfonyl}-4,6-d...)copy SMILEScopy InChI
Affinity DataKi:  156nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23341(1-{6-chloro-12-oxo-11,17-diazatetracyclo[11.3.1.0^...)copy SMILEScopy InChI
Affinity DataKi:  171nM ΔG°:  -8.92kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23323(3,3-dimethyl-1-[(2S)-2-(4-phenylbutanoyl)pyrrolidi...)copy SMILEScopy InChI
Affinity DataKi:  180nM ΔG°:  -8.42kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9G7GPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23389(N-(6-fluoropyridin-3-yl)-6-methoxy-12-oxo-11,17-di...)copy SMILEScopy InChI
Affinity DataKi:  183nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23342(1-{4-fluoro-12-oxo-11,17-diazatetracyclo[11.3.1.0^...)copy SMILEScopy InChI
Affinity DataKi:  201nM ΔG°:  -8.82kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23363(17-[2-(4-chlorophenyl)-2-hydroxyacetyl]-4,6-dimeth...)copy SMILEScopy InChI
Affinity DataKi:  208nM ΔG°:  -8.80kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23325(3,3-dimethyl-1-[(2S)-2-[5-(pyridin-3-yl)pentanoyl]...)copy SMILEScopy InChI
Affinity DataKi:  210nM ΔG°:  -8.34kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9G7GPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23390(6-methoxy-N-(6-methoxypyridin-3-yl)-12-oxo-11,17-d...)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23343(1-{12-oxo-11,17-diazatetracyclo[11.3.1.0^{2,11}.0^...)copy SMILEScopy InChI
Affinity DataKi:  217nM ΔG°:  -8.78kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23344(1-{5-fluoro-12-oxo-11,17-diazatetracyclo[11.3.1.0^...)copy SMILEScopy InChI
Affinity DataKi:  225nM ΔG°:  -8.76kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23391(6-methoxy-12-oxo-N-(3,4,5-trifluorophenyl)-11,17-d...)copy SMILEScopy InChI
Affinity DataKi:  236nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23356(1-{4,6-dimethoxy-12-oxo-11,17-diazatetracyclo[11.3...)copy SMILEScopy InChI
Affinity DataKi:  238nM ΔG°:  -8.73kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23324(1-[(2S)-2-[5-(4-hydroxyphenyl)pentanoyl]pyrrolidin...)copy SMILEScopy InChI
Affinity DataKi:  240nM ΔG°:  -8.27kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9G7GPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23379(17-(benzenesulfonyl)-4,6-dimethoxy-11,17-diazatetr...)copy SMILEScopy InChI
Affinity DataKi:  244nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23380(17-[(4-ethylbenzene)sulfonyl]-4,6-dimethoxy-11,17-...)copy SMILEScopy InChI
Affinity DataKi:  266nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23370(1-{4,6-dimethoxy-12-oxo-11,17-diazatetracyclo[11.3...)copy SMILEScopy InChI
Affinity DataKi:  279nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23357(1-(2,3-dichlorophenyl)-2-{4,6-dimethoxy-12-oxo-11,...)copy SMILEScopy InChI
Affinity DataKi:  282nM ΔG°:  -8.63kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bos taurus (bovine))
Guilford Pharmaceuticals, Inc.

LigandPNGBDBM23381(4,6-dimethoxy-17-({4-[(3,4,5-trimethoxyphenyl)amin...)copy SMILEScopy InChI
Affinity DataKi:  288nMAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8QG9PubMed
Displayed 1 to 50 (of 79 total ) | Next | Last >>
Jump to: